EGO PGX1401PB handleiding
Handleiding
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- Polyethylene: No test substance-related toxic effects were observed in an acute oral toxicity study with rats.
- Carbon black: No effect on endothelins or blood pressure was observed after exposure to carbon black. There were
also no effects on body temperature and activity of the animals.
- Nickel; Raney nickel: In the acute oral toxicity using rat, there were no effects on clinical signs, systemic
toxicity.(OECD Guideline 401, GLP)
- Chromium: In the acute oral toxicity using rat, salivation increased among all animals 15 minutes after
administration of the test substance, and lasted about 8 hours. (OECD TG 420, GLP)
- Ethylbenzene: In acute oral, inhalation, dermal toxicity study with rats, adverse effects were not observed related
to acute toxicity.
Specific target organ toxicity (repeat exposure):
- Fe: Rats were exposed to metallic iron as carbonyl iron via their feed (2.5%) for 2, 4, 6, or 9 weeks. This resulted
in a strong increase of non-heme iron in the liver and clear lipid peroxidation in the liver and the mucosa of the
duodenum. No evidence for DNA breakage were found. What follows is the original abstract of the publication.
(carbonyl iron)
- Copper: In test with rats for 92 days, there were no mortalities or signs of clinical toxicity observed in any of the
test species during the duration of the study. Opthalmoscopic examinations revealed no abnormalities at any dose
level tested. At gross pathology, significant decreases in heart and kidney weight were noted in the high dose males
in the thymus and kidneys of high dose females. (GLP)
- Aluminum: On occasion workers chronically exposed to aluminum-containing dusts or fumes have developed
severe pulmonary reactions including fibrosis, emphysema and pneumothorax.
- Lithium hexafluorophosphate(1-): According to expert review of fluoride intake and effects on human health,
fluoride intake in drinking water at levels close to or above 4 mg/l is associated with dental fluorosis and perhaps
also bone fluorosis and/or weakening.; Damage to dental enamel recorded: especially notable in young animals,
which also showed atrophy of respiratory organs/tissues with local oedema of bronchial mucosa. Older animals
showed peribronchial hyperplasia. Animals around 1 year in age showed cavity formation in their
bones.(Information on major hydrolysis product of the registered substance (released rapidly on contact with
water/moisture))(OECD Guideline 412)
- Polyethylene: No significant adverse effects were observed in subchronic (90-day) oral toxicity study with rats and
dogs.
- Boehmite (Al(OH)O): There were no clear clinical signs or observations during necropsy which could be related
to the treatment.(OECD Guideline 408, GLP), Intratracheal injection of aluminium powder caused nodular
pulmonary fibrosis in the lungs of the rats only at the highest dose administered (100 mg).(OECD Guideline 413)
- Carbon black: Mice were continuously fed various types of carbon black in massive quantities (10% in diet) for 12
to 18 months. This led to no detectable changes from the normal in the organs and tissues of the mice fed.
- Nickel; Raney nickel: In nickel plating industry, exposure to nickel containing vapors has been reported to be
assoc with asthma.
- Chromium: In the repeated Dose 90-Day Oral toxicity test using rat, there were no effects on clinical signs,
mortality.
- Ethylbenzene: In repeated oral toxicity study with rats for 28 days, increased liver weight and hepatocellular
hypertrophy at higher dose levels were observed. (NOEAL = 75 mg/kg bw/day) (OECD TG407, GLP); In repeated
inhalation toxicity study with rats for 13 weeks, increases in liver and kidney weights but no other treatment related
effects were observed in rats that inhaled >=250 ppm ethylbenzene vapour for 13 weeks, NOAEC = 1000ppm
(OECD Guideline 413, GLP), Classified as Category 2 according to EU GHS
Aspiration Hazard:
- Ethylbenzene: Classified as Category 1 according to EU GHS
12. ECOLOGICAL INFORMATION
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Productinformatie
| Merk | EGO |
| Model | PGX1401PB |
| Categorie | Niet gecategoriseerd |
| Taal | Nederlands |
| Grootte | 3256 MB |
